ID   PathHunter HEK 293 CCKAR beta-arrestin
AC   CVCL_KZ37
DR   DiscoverX; 93-0190C1
DR   Wikidata; Q54938017
CC   Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1570; CCKAR.
CC   Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 22-08-17; Last updated: 14-08-25; Version: 10
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