ID PathHunter HEK 293 ADRA1D(82-572) beta-arrestin AC CVCL_KZ31 DR DiscoverX; 93-0983C1 DR Wikidata; Q54938009 CC Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal. CC Genetic integration: Method=Transfection; Gene=HGNC; HGNC:280; ADRA1D. CC Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2. CC Transformant: NCBI_TaxID; 28285; Adenovirus 5. CC Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. OX NCBI_TaxID=9606; ! Homo sapiens (Human) HI CVCL_0045 ! HEK293 SX Female AG Fetus CA Transformed cell line DT Created: 22-08-17; Last updated: 19-12-24; Version: 8 //