ID   PathHunter CHO-K1 OXGR1 beta-arrestin
AC   CVCL_KY72
DR   DiscoverX; 93-0693C2
DR   Wikidata; Q54937932
CC   Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4531; OXGR1.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 10
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