ID   PathHunter C2C12 TACR1 beta-arrestin
AC   CVCL_KW21
DR   DiscoverX; 93-0344C7
DR   Wikidata; Q54937594
CC   Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:712; ARRB2.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11526; TACR1.
CC   Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134.
CC   Cell type: Myoblast; CL=CL_0000056.
CC   Breed/subspecies: C3H.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0188 ! C2C12
SX   Female
AG   2M
CA   Spontaneously immortalized cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 11
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