ID   PathHunter BHK-21 rPTGER4 beta-arrestin
AC   CVCL_KW17
DR   DiscoverX; 93-0908C16
DR   Wikidata; Q54937590
CC   Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
CC   Genetic integration: Method=Transfection; Gene=RGD; 628641; Ptger4.
CC   Genetic integration: Method=Transfection; Gene=HGNC; 712; ARRB2.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=10036; ! Mesocricetus auratus (Golden hamster)
HI   CVCL_1915 ! BHK-21 clone 13
SX   Male
AG   1D
CA   Spontaneously immortalized cell line
DT   Created: 22-08-17; Last updated: 10-09-24; Version: 7
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