ID   A549/NFkB-luc
AC   CVCL_KS36
DR   cancercelllines; CVCL_KS36
DR   Wikidata; Q54607050
RX   PubMed=16834536;
CC   Population: Caucasian.
CC   Characteristics: The luciferase reporter gene is under the control of multiple copies of the NF-kappaB response element (PubMed=16834536).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Discontinued: Thermo Fisher/Panomics; Catalog number RC0002.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 15
//
RX   PubMed=16834536; DOI=10.1089/adt.2006.4.307;
RA   Lai C.-F., Jiang X., Li X.-Q.;
RT   "Development of luciferase reporter-based cell assays.";
RL   Assay Drug Dev. Technol. 4:307-315(2006).
//