ID   YUSWI
AC   CVCL_K024
DR   cancercelllines; CVCL_K024
DR   Wikidata; Q54995824
RX   PubMed=22842228;
RX   PubMed=26214590;
CC   Part of: Yale University (YU) melanoma cell collection.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26214590).
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: Metastatic; Small intestine; UBERON=UBERON_0002108.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 18
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RX   PubMed=22842228; DOI=10.1038/ng.2359; PMCID=PMC3432702;
RA   Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A.,
RA   McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., Ariyan S.,
RA   Narayan D., Dutton-Regester K., Capatana A., Holman E.C.,
RA   Bosenberg M.W., Sznol M., Kluger H.M., Brash D.E., Stern D.F.,
RA   Materin M.A., Lo R.S., Mane S.M., Ma S.-G., Kidd K.K., Hayward N.K.,
RA   Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.;
RT   "Exome sequencing identifies recurrent somatic RAC1 mutations in
RT   melanoma.";
RL   Nat. Genet. 44:1006-1014(2012).
//
RX   PubMed=26214590; DOI=10.1038/ng.3361; PMCID=PMC4916843;
RA   Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N.,
RA   Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M.,
RA   Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S.M.,
RA   Schlessinger J., Lifton R.P., Halaban R.;
RT   "Exome sequencing identifies recurrent mutations in NF1 and RASopathy
RT   genes in sun-exposed melanomas.";
RL   Nat. Genet. 47:996-1002(2015).
//