ID   Jurkat-F9-1906LUC
AC   CVCL_JZ99
SY   J-1906-F9
DR   cancercelllines; CVCL_JZ99
DR   Wikidata; Q54899155
RX   Patent=US20040152126;
RX   Patent=WO2001004350A1;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, European Collection of Cell Cultures (ECACC); 99032405.
CC   Population: Caucasian.
CC   Characteristics: Transfected with luciferase under the control of the PTGS2/COX-2 promoter.
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 14-08-25; Version: 19
//
RX   Patent=WO2001004350A1;
RA   Fresno Escudero, Manuel
RA   Iniguez-Pena, Miguel Angel
RT   "Cell line comprising the promoter of cyclooxygenase-2 (COX-2) and a
RT   witness gene, and use thereof in the search of COX-2 transcriptional
RT   induction selective inhibitors.";
RL   Patent number WO2001004350A1, 18-Jan-2001.
//
RX   Patent=US20040152126;
RA   Fresno Escudero, Manuel
RA   Iniguez-Pena, Miguel Angel
RT   "Methods of screening for COX-2 inhibitors.";
RL   Patent number US20040152126, 05-Aug-2004.
//