ID   M21L
AC   CVCL_JZ12
SY   M21-L; M21-Low
DR   cancercelllines; CVCL_JZ12
DR   Wikidata; Q54903521
RX   PubMed=1376331;
RX   PubMed=2447074;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-389.html
CC   Characteristics: Lacks expression of integrin alpha-V (ITGAV).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D031 ! M21
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 9
//
RX   PubMed=1376331; DOI=10.1172/JCI115811; PMCID=PMC295910;
RA   Felding-Habermann B., Mueller B.M., Romerdahl C.A., Cheresh D.A.;
RT   "Involvement of integrin alpha V gene expression in human melanoma
RT   tumorigenicity.";
RL   J. Clin. Invest. 89:2018-2022(1992).
//
RX   PubMed=2447074; DOI=10.1016/S0021-9258(18)45436-1;
RA   Cheresh D.A., Spiro R.C.;
RT   "Biosynthetic and functional properties of an Arg-Gly-Asp-directed
RT   receptor involved in human melanoma cell attachment to vitronectin,
RT   fibrinogen, and von Willebrand factor.";
RL   J. Biol. Chem. 262:17703-17711(1987).
//