ID   H357-VB6
AC   CVCL_JY68
SY   VB6
DR   Wikidata; Q54992947
RX   PubMed=11340566;
RX   PubMed=11442751;
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Ser (c.37G>A); ClinVar=VCV000376323; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6150; ITGAV.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6161; ITGB6.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_JY67 ! H357-V3
SX   Male
AG   74Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 19-12-24; Version: 12
//
RX   PubMed=11442751; DOI=10.1046/j.0022-202x.2001.01379.x;
RA   Thomas, Gareth J.
RA   Lewis, Mark P.
RA   Whawell, Simon A.
RA   Russell, Alan
RA   Sheppard, Dean
RA   Hart, Ian R.
RA   Speight, Paul M.
RA   Marshall, John F.
RT   "Expression of the alphavbeta6 integrin promotes migration and
RT   invasion in squamous carcinoma cells.";
RL   J. Invest. Dermatol. 117:67-73(2001).
//
RX   PubMed=11340566; DOI=10.1002/1097-0215(20010601)92:5<641::AID-IJC1243>3.0.CO;2-P;
RA   Thomas, Gareth J.
RA   Lewis, Mark P.
RA   Hart, Ian R.
RA   Marshall, John F.
RA   Speight, Paul M.
RT   "AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells
RT   through up-regulation of matrix metalloproteinase-9.";
RL   Int. J. Cancer 92:641-650(2001).
//