ID   14433_1
AC   CVCL_JY31
SY   14433
DR   cancercelllines; CVCL_JY31
DR   Wikidata; Q54581913
RX   PubMed=25862976;
RX   PubMed=31150822;
CC   Doubling time: 2-3 days (PubMed=25862976).
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys2853Ter (c.8557A>T); ClinVar=VCV000372573; Zygosity=Homozygous (PubMed=25862976; PubMed=31150822).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Unspecified; Note=Splice donor mutation (PubMed=25862976; PubMed=31150822).
CC   Omics: Genomics; Whole genome sequencing; Low read coverage.
CC   Omics: Transcriptomics; RNAseq.
CC   Miscellaneous: Age at sampling and TP53 mutation cDNA coordinates from personal communication of Castillo-Tong, Dan Cacsire.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): PubMed=31150822
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D12S391: 21
ST   D13S317: 11
ST   D16S539: 12
ST   D18S51: 18
ST   D19S433: 14,15
ST   D1S1656: 12,19.3
ST   D21S11: 29,30
ST   D2S1338: 22
ST   D3S1358: 15
ST   D5S818: 11,12
ST   D6S1043: 20
ST   D7S820: 8,10
ST   D8S1179: 14,15
ST   FGA: 21
ST   Penta D: 9,10
ST   Penta E: 14
ST   TH01: 8
ST   TPOX: 10,11
ST   vWA: 17
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 14
//
RX   PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032;
RA   Kreuzinger, Caroline
RA   von der Decken, Isabel
RA   Wolf, Andrea
RA   Gamperl, Magdalena
RA   Koller, Julia
RA   Karacs, Jasmine
RA   Pfaffinger, Stephanie
RA   Bartl, Thomas
RA   Reinthaller, Alexander
RA   Grimm, Christoph
RA   Singer, Christian F.
RA   Braicu, Elena Ioana
RA   Cunnea, Paula
RA   Gourley, Charlie
RA   Smeets, Dominiek
RA   Boeckx, Bram
RA   Lambrechts, Diether
RA   Perco, Paul
RA   Horvat, Reinhard
RA   Berns, Els M.J.J.
RA   Castillo-Tong, Dan Cacsire
RT   "Patient-derived cell line models revealed therapeutic targets and
RT   molecular mechanisms underlying disease progression of high grade
RT   serous ovarian cancer.";
RL   Cancer Lett. 459:1-12(2019).
//
RX   PubMed=25862976; DOI=10.1016/j.canlet.2015.03.040;
RA   Kreuzinger, Caroline
RA   Gamperl, Magdalena
RA   Wolf, Andrea
RA   Heinze, Georg
RA   Geroldinger, Angelika
RA   Lambrechts, Diether
RA   Boeckx, Bram
RA   Smeets, Dominiek
RA   Horvat, Reinhard
RA   Aust, Stefanie
RA   Hamilton, Gerhard
RA   Zeillinger, Robert
RA   Castillo-Tong, Dan Cacsire
RT   "Molecular characterization of 7 new established cell lines from high
RT   grade serous ovarian cancer.";
RL   Cancer Lett. 362:218-228(2015).
//