ID   TTNT-1
AC   CVCL_JX67
DR   Wikidata; Q54973294
RX   Patent=US7521234;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-7498.
CC   Characteristics: Because it has been transduced by a construct containing LoxP sites, transfection with the Cre recombinase eliminates the SV40 T gene thus reverting the cells to a non-immortal phenotype.
CC   Characteristics: Transduced with a retroviral vector SSR#197 (MoMLV/LTR-LoxP-hTERT-IRES-EGFP-LoxP-MoMLV/LTR) expressing hTERT and eGFP flanked by a pair of loxP sites.
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Telomerase immortalized cell line
DT   Created: 22-08-17; Last updated: 29-06-23; Version: 6
//
RX   Patent=US7521234;
RA   Kobayashi N., Leboulch P., Tanaka N., Fujiwara T., Totsugawa T.;
RT   "Mammalian immortalized liver cell.";
RL   Patent number US7521234, 21-Apr-2009.
//