ID   MUG-Mel2
AC   CVCL_JQ50
SY   MUG-MEL2; MUG Mel2; MUGMel2; Medical University of Graz-Melanoma 2
DR   cancercelllines; CVCL_JQ50
DR   ChEMBL-Cells; CHEMBL4630708
DR   ChEMBL-Targets; CHEMBL4630714
DR   DSMZ; ACC-855
DR   DSMZCellDive; ACC-855
DR   PubChem_Cell_line; CVCL_JQ50
DR   Wikidata; Q54907057
RX   PubMed=28522871;
CC   Characteristics: Highly pigmented. Tumorigenic in nude mice.
CC   Doubling time: 38.19 +- 4.09 hours (PubMed=28522871); ~48 hours (DSMZ=ACC-855).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=28522871).
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: In situ; Shoulder, skin; UBERON=UBERON_0001483.
ST   Source(s): DSMZ=ACC-855; PubMed=28522871
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 10,11
ST   D18S51: 13
ST   D19S433: 14
ST   D21S11: 29,31.2
ST   D2S1338: 17 (PubMed=28522871)
ST   D2S1338: 17,20 (DSMZ=ACC-855)
ST   D3S1358: 14,15
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 13,15
ST   FGA: 22
ST   Penta D: 9,13
ST   Penta E: 7,14
ST   TH01: 9.3
ST   TPOX: 9,11
ST   vWA: 15,17
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   48Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 15
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RX   PubMed=28522871; DOI=10.1038/s41598-017-02197-y; PMCID=PMC5437015;
RA   Rinner B., Gandolfi G., Meditz K., Frisch M.-T., Wagner K.,
RA   Ciarrocchi A., Torricelli F., Koivuniemi R.J., Niklander J.,
RA   Liegl-Atzwanger B., Lohberger B., Heitzer E.,
RA   Ghaffari-Tabrizi-Wizsy N., Zweytick D., Zalaudek I.;
RT   "MUG-Mel2, a novel highly pigmented and well characterized NRAS
RT   mutated human melanoma cell line.";
RL   Sci. Rep. 7:2098-2098(2017).
//