ID   TIN2 F/F
AC   CVCL_JM07
DR   ATCC; CRL-3318
DR   Wikidata; Q54972491
RX   PubMed=22099311;
CC   Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 1st coding exon of mouse Terf1 gene. Terf1 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3318).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 15-05-17; Last updated: 14-08-25; Version: 9
//
RX   PubMed=22099311; DOI=10.1016/j.molcel.2011.08.043; PMCID=PMC3222871;
RA   Takai, Kaori K.
RA   Kibe, Tatsuya
RA   Donigian, Jill R.
RA   Frescas, David
RA   de Lange, Titia
RT   "Telomere protection by TPP1/POT1 requires tethering to TIN2.";
RL   Mol. Cell 44:647-659(2011).
//