ID   K-562-GFP
AC   CVCL_JM00
DR   ATCC; CCL-243-GFP
DR   Wikidata; Q54899220
RX   CelloPub=CLPUB00577;
WW   Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/population-doubling-time-of-k-562-gfp
CC   Population: Caucasian.
CC   Characteristics: Stably expresses GFP under the control of the human EF1a promoter.
CC   Doubling time: 18-24 hours (ATCC=CCL-243-GFP).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): ATCC=CCL-243-GFP
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 8
ST   D16S539: 11,12
ST   D5S818: 11,12
ST   D7S820: 9,11
ST   TH01: 9.3
ST   TPOX: 8,9
ST   vWA: 16
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 10-04-25; Version: 20
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RX   CelloPub=CLPUB00577;
RA   McWilliams-Koeppen H.P., Clinton J.;
RT   "A simple and rapid alternative to 51chromium or fluorescent dye
RT   loading for quantification of natural killer cell activity: ATCC
RT   K-562-GFP cells.";
RL   (In technical document) ATCC application note 31; pp.1-8; ATCC; Manassas; USA (2017).
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