ID   HeLa-X4
AC   CVCL_JL48
SY   HeLa-X4-6
DR   Wikidata; Q54882735
RX   PubMed=16314403;
CC   Population: African American.
CC   Characteristics: Engineered to express the gp160 envelope protein (Env) from a CXCR4-tropic HIV-1 isolate.
CC   Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
CC   Transfected with: HIV-1 isolate NL4-3 env.
CC   Transfected with: UniProtKB; P04610; HIV-1 isolate BRU/LAI tat.
CC   Transfected with: UniProtKB; P42212; GFP.
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_IY74 ! HeLa Tet-On
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 05-10-23; Version: 10
//
RX   PubMed=16314403; DOI=10.1177/1087057105282959;
RA   Ji C.-H., Zhang J., Cammack N., Sankuratri S.;
RT   "Development of a novel dual CCR5-dependent and CXCR4-dependent
RT   cell-cell fusion assay system with inducible gp160 expression.";
RL   J. Biomol. Screen. 11:65-74(2006).
//