ID   La-K4DT
AC   CVCL_JH76
SY   Lowland anoa K4DT
DR   Wikidata; Q54899288
RX   PubMed=27449922;
CC   Group: Endangered species/breed cell line.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Caution: Title and abstract of paper (PubMed=27449922) states that cell line is from Bubalus quarlesi, but text correctly indicates this cell line is from Bubalus depressicornis.
CC   Derived from site: In situ; Ear, skin; UBERON=UBERON_0001459.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=27596; ! Bubalus depressicornis (Lowland anoa)
OI   CVCL_E3SL ! La-K4D
SX   Female
AG   31Y
CA   Telomerase immortalized cell line
DT   Created: 15-05-17; Last updated: 19-12-24; Version: 9
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RX   PubMed=27449922; DOI=10.1007/s10616-016-0004-0; PMCID=PMC5023572;
RA   Fukuda T., Iino Y., Eitsuka T., Onuma M., Katayama M., Murata K.,
RA   Inoue-Murayama M., Hara K., Isogai E., Kiyono T.;
RT   "Cellular conservation of endangered midget buffalo (Lowland Anoa,
RT   Bubalus quarlesi) by establishment of primary cultured cell, and its
RT   immortalization with expression of cell cycle regulators.";
RL   Cytotechnology 68:1937-1947(2016).
//