ID   Hep-2040
AC   CVCL_JG91
SY   Hep2040
DR   JCRB; JCRB1701
DR   Wikidata; Q54882762
RX   PubMed=33060611;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Discontinued: JCRB; JCRB1701; probable.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
ST   Source(s): JCRB=JCRB1701
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 9,11
ST   D5S818: 11,12
ST   D7S820: 11
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 16,18
DI   NCIt; C84400; Intrahepatic cholestasis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   7M
CA   Telomerase immortalized cell line
DT   Created: 15-05-17; Last updated: 19-12-24; Version: 13
//
RX   PubMed=33060611; DOI=10.1038/s41598-020-73992-3; PMCID=PMC7567112;
RA   Nishiwaki, Manami
RA   Toyoda, Masashi
RA   Oishi, Yoshie
RA   Ishida, Seiichi
RA   Horiuchi, Shin-ichiro
RA   Makino-Itou, Hatsune
RA   Kimura, Tohru
RA   Ohno, Shin-ichi
RA   Ohkura, Takashi
RA   Enosawa, Shin
RA   Akutsu, Hidenori
RA   Nakazawa, Atsuko
RA   Kasahara, Mureo
RA   Kiyono, Tohru
RA   Umezawa, Akihiro
RT   "Immortalization of human hepatocytes from biliary atresia with
RT   CDK4(R24C), cyclin D1, and TERT for cytochrome P450 induction
RT   testing.";
RL   Sci. Rep. 10:17503.1-17503.13(2020).
//