ID   vdR2-4
AC   CVCL_JG31
DR   JCRB; JCRB1658
DR   Wikidata; Q54992977
WW   Info; EGTC; -; https://web.archive.org/web/20201202094525/http://egtc.jp/action/access/cellline_detail?cellline=vdR2-4+
CC   Characteristics: Both alleles of Blm locus were modified for tetracycline-dependent gene regulation. A 4-hydroxytamoxifen-regulatable Cre recombinase, ERT2-Cre-ERT2 was knocked into the Rosa26 locus for constitutive expression.
CC   Genetic integration: Method=Homologous recombination; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2).
CC   Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: C57BL/6 x 129S4/SvJae.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_C865 ! v6.5
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 15-05-17; Last updated: 10-04-25; Version: 6
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