ID   ED-40515(-)
AC   CVCL_JF70
DR   RCB; RCB3534
DR   Wikidata; Q54831950
RX   PubMed=7662981;
RX   PubMed=32210945;
CC   Population: Japanese.
CC   Characteristics: Lost its original IL2 dependency.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3184; Adult T-cell leukemia/lymphoma
DI   ORDO; Orphanet_86875; Adult T-cell leukemia/lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_JF68 ! ED-40515
SX   Male
AG   34Y
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 29-06-23; Version: 10
//
RX   PubMed=7662981; DOI=10.1182/blood.V86.6.2350.bloodjournal8662350;
RA   Imada K., Takaori-Kondo A., Akagi T., Shimotohno K., Sugamura K.,
RA   Hattori T., Yamabe H., Okuma M., Uchiyama T.;
RT   "Tumorigenicity of human T-cell leukemia virus type I-infected cell
RT   lines in severe combined immunodeficient mice and characterization of
RT   the cells proliferating in vivo.";
RL   Blood 86:2350-2357(1995).
//
RX   PubMed=32210945; DOI=10.3389/fmicb.2020.00356;
RA   Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i.,
RA   Usami K., Shimizu A., Matsuoka M.;
RT   "IL-2/IL-2 receptor pathway plays a crucial role in the growth and
RT   malignant transformation of HTLV-1-infected T cells to develop adult
RT   T-cell leukemia.";
RL   Front. Microbiol. 11:356.1-356.17(2020).
//