ID   FM3A tsFT101
AC   CVCL_J378
SY   FM3A FT-101; tsFT101
DR   CLO; CLO_0050961
DR   JCRB; JCRB0706
DR   RCB; RCB0032
DR   Wikidata; Q54835034
RX   PubMed=2581712;
RX   PubMed=9211798;
RX   PubMed=33187357;
CC   Characteristics: Temperature sensitive phenotype. Cytokinesis is blocked at 39 Celsius.
CC   Sequence variation: Mutation; MGI; MGI:1927222; Diaph3; Simple; p.Ile733Asn (c.2198T>A); Zygosity=Homozygous (PubMed=33187357).
CC   Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: C3H/He.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3869 ! FM3A
SX   Female
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 29-06-23; Version: 9
//
RX   PubMed=2581712; DOI=10.1247/csf.10.79;
RA   Yasumitsu H., Hanaoka F., Yasuda H., Murakami Y., Enomoto T.,
RA   Yamada M.-a.;
RT   "Isolation and initial characterization of a temperature-sensitive
RT   mutant of mouse FM3A cells defective in cytokinesis.";
RL   Cell Struct. Funct. 10:79-88(1985).
//
RX   PubMed=9211798; DOI=10.1007/s004240050406;
RA   Cao Y., Motomura K., Ohtsuru A., Matsumoto T., Yamashita S.,
RA   Kosaka M.;
RT   "Profilin gene expression and regulation in a temperature-sensitive
RT   breast cancer cell line: tsFT101.";
RL   Pflugers Arch. 434:341-345(1997).
//
RX   PubMed=33187357; DOI=10.3390/ijms21228493;
RA   Kazama H., Kashiwaba S.-i., Ishii S., Yoshida K., Yatsuo Y.,
RA   Naraoka T., Fukuoka M., Murakami Y.;
RT   "Loss of DIAPH3, a formin family protein, leads to cytokinetic failure
RT   only under high temperature conditions in mouse FM3A cells.";
RL   Int. J. Mol. Sci. 21:8493.1-8493.17(2020).
//