ID   SK-MEL-28-Luc
AC   CVCL_J267
DR   cancercelllines; CVCL_J267
DR   JCRB; JCRB1376
DR   JCRB; NIHS0641
DR   Wikidata; Q54954015
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Arg24Cys (c.70C>T); ClinVar=VCV000016928; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Pro753Ser (c.2257C>T); ClinVar=VCV000376081; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr167Ala (c.499A>G); ClinVar=VCV001686107; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.-57A>C (c.161A>C) (A161C); ClinVar=VCV000242210; Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu145Arg (c.434T>G); ClinVar=VCV001027110; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Discontinued: JCRB; NIHS0641; true.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Melanocyte of skin; CL=CL_1000458.
ST   Source(s): JCRB=JCRB1376
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 11,12
ST   D16S539: 9,12
ST   D5S818: 13
ST   D7S820: 9.3,10
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 19
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0526 ! SK-MEL-28
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 14-08-25; Version: 26
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