ID   KM12-Luc
AC   CVCL_J258
SY   KM-12-Luc
DR   cancercelllines; CVCL_J258
DR   JCRB; JCRB1389
DR   JCRB; NIHS0647
DR   Wikidata; Q54900059
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 8031; NTRK1 + HGNC; 12012; TPM3; Name(s)=TPM3-NTRK1 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Asn1819fs*7 (c.5454_5455insA); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1101; BRCA2; Simple; p.Asn1784Hisfs*7 (c.5350_5351delAA); ClinVar=VCV000037959; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Gly129Ter (c.385G>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val73Trpfs*50 (c.216delC) (p.P72fs); ClinVar=VCV000428897; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Arg (c.536A>G); ClinVar=VCV000376606; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Discontinued: JCRB; NIHS0647; true.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): JCRB
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12,15,16
ST   D16S539: 11
ST   D5S818: 10,18,19
ST   D7S820: 8,8.3
ST   TH01: 9.3
ST   TPOX: 11,12
ST   vWA: 17,19
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1331 ! KM12
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 17
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