ID   ST88-3
AC   CVCL_IU70
SY   88-3; NF188-3
DR   Wikidata; Q54955755
RX   PubMed=1568246;
RX   PubMed=1906341;
RX   PubMed=10791998;
RX   PubMed=16510576;
RX   PubMed=28469964;
DI   NCIt; C3798; Malignant peripheral nerve sheath tumor
DI   NCIt; C3273; Neurofibromatosis type 1
DI   ORDO; Orphanet_3148; Malignant peripheral nerve sheath tumor
DI   ORDO; Orphanet_636; Neurofibromatosis type 1
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 21-03-23; Version: 6
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RX   PubMed=1568246; DOI=10.1016/0092-8674(92)90407-4;
RA   DeClue J.E., Papageorge A.G., Fletcher J.A., Diehl S.R., Ratner N.,
RA   Vass W.C., Lowy D.R.;
RT   "Abnormal regulation of mammalian p21ras contributes to malignant
RT   tumor growth in von Recklinghausen (type 1) neurofibromatosis.";
RL   Cell 69:265-273(1992).
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RX   PubMed=1906341; DOI=10.1002/gcc.2870030111;
RA   Glover T.W., Stein C.K., Legius E., Andersen L.B., Brereton A.,
RA   Johnson S.;
RT   "Molecular and cytogenetic analysis of tumors in von Recklinghausen
RT   neurofibromatosis.";
RL   Genes Chromosomes Cancer 3:62-70(1991).
//
RX   PubMed=10791998; DOI=10.1172/JCI7610;
RA   DeClue J.E., Heffelfinger S.C., Benvenuto G., Ling B., Li S.-W., Rui W.,
RA   Vass W.C., Viskochil D., Ratner N.;
RT   "Epidermal growth factor receptor expression in neurofibromatosis type
RT   1-related tumors and NF1 animal models.";
RL   J. Clin. Invest. 105:1233-1241(2000).
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RX   PubMed=16510576; DOI=10.1158/0008-5472.CAN-05-3330;
RA   Miller S.J., Rangwala F., Williams J., Ackerman P., Kong S.,
RA   Jegga A.G., Kaiser S., Aronow B.J., Frahm S., Kluwe L., Mautner V.-F.,
RA   Upadhyaya M., Muir D.F. IV, Wallace M.R., Hagen J., Quelle D.E.,
RA   Watson M.A., Perry A., Gutmann D.H., Ratner N.;
RT   "Large-scale molecular comparison of human Schwann cells to malignant
RT   peripheral nerve sheath tumor cell lines and tissues.";
RL   Cancer Res. 66:2584-2591(2006).
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RX   PubMed=28469964;
RA   Guo J.-M., Grovola M.R., Xie H., Coggins G.E., Duggan P., Hasan R.,
RA   Huang J.-L., Lin D.W., Song C., Witek G.M., Berritt S., Schultz D.C.,
RA   Field J.;
RT   "Comprehensive pharmacological profiling of neurofibromatosis cell
RT   lines.";
RL   Am. J. Cancer Res. 7:923-934(2017).
//