ID   KNBCCS6
AC   CVCL_IU64
DR   Wikidata; Q54900246
RX   Patent=US20190242874;
RX   PubMed=18679421;
CC   Sequence variation: Mutation; HGNC; 9585; PTCH1; Simple; p.Pro643Thrfs*11 (c.1925insC) (H652X); Zygosity=Heterozygous (PubMed=18679421).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
DI   NCIt; C2892; Nevoid basal cell carcinoma syndrome
DI   ORDO; Orphanet_377; Gorlin syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   49Y
CA   Finite cell line
DT   Created: 03-03-17; Last updated: 29-06-23; Version: 10
//
RX   Patent=US20190242874;
RA   Burty E., Magnaldo T., Gache Y., Aubert J.;
RT   "Human epithelial cell line for 3-D modelizing of cancer and treatment
RT   thereof.";
RL   Patent number US20190242874, 08-Aug-2019.
//
RX   PubMed=18679421; DOI=10.1038/onc.2008.260;
RA   Brellier F., Bergoglio V., Valin A., Barnay-Verdier S.,
RA   Chevallier-Lagente O., Vielh P., Spatz A., Gorry P., Avril M.-F.,
RA   Magnaldo T.;
RT   "Heterozygous mutations in the tumor suppressor gene PATCHED provoke
RT   basal cell carcinoma-like features in human organotypic skin
RT   cultures.";
RL   Oncogene 27:6601-6606(2008).
//