ID   HLY-1 eIF4E1
AC   CVCL_IN94
DR   GEO; GSM1511349
DR   GEO; GSM1511350
DR   GEO; GSM1511351
DR   GEO; GSM1511361
DR   GEO; GSM1511362
DR   GEO; GSM1511363
DR   Wikidata; Q54889871
RX   PubMed=25403230;
CC   Sequence variation: Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Ser206Cys (c.617C>G) (p.Ser219Cys, c.656C>G) (S219C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3287; EIF4E.
CC   Omics: Transcriptomics; Microarray.
DI   NCIt; C36081; Diffuse large B-cell lymphoma activated B-cell type
DI   ORDO; Orphanet_544; Diffuse large B-cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_H207 ! HLY-1
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-03-17; Last updated: 10-04-25; Version: 10
//
RX   PubMed=25403230; DOI=10.1038/ncomms6413; PMCID=PMC4238046;
RA   Landon A.L., Muniandy P.A., Shetty A.C., Lehrmann E., Volpon L.,
RA   Houng S., Zhang Y.-Q., Dai B.-J., Peroutka R.J. 3rd, Mazan-Mamczarz K.,
RA   Steinhardt J., Mahurkar A., Becker K.G., Borden K.L.B.,
RA   Gartenhaus R.B.;
RT   "MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA
RT   translation in DLBCL.";
RL   Nat. Commun. 5:5413.1-5413.15(2014).
//