ID   OVCAR-8 RIA
AC   CVCL_IM65
DR   cancercelllines; CVCL_IM65
DR   GEO; GSM322537
DR   GEO; GSM322538
DR   GEO; GSM322539
DR   Wikidata; Q54937016
RX   PubMed=18822129;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Gln26Arg (c.77A>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3430; ERBB2; Simple; p.Gly776Val (c.2327G>T); ClinVar=VCV000163410; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Pro121His (c.362C>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 9388; PRKAR1A.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1629 ! OVCAR-8
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 01-12-16; Last updated: 10-09-24; Version: 13
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RX   PubMed=18822129; DOI=10.1186/1755-8794-1-43; PMCID=PMC2577111;
RA   Cheadle C., Nesterova M., Watkins T., Barnes K.C., Hall J.C.,
RA   Rosen A., Becker K.G., Cho-Chung Y.S.;
RT   "Regulatory subunits of PKA define an axis of cellular
RT   proliferation/differentiation in ovarian cancer cells.";
RL   BMC Med. Genomics 1:43.1-43.14(2008).
//