ID   Mac-2A
AC   CVCL_H637
SY   MAC-2A; MAC2A; McG-2A; PB-2A
DR   cancercelllines; CVCL_H637
DR   Cell_Model_Passport; SIDM01361
DR   Cosmic; 2814457
DR   DepMap; ACH-001119
DR   GEO; GSM2527946
DR   Wikidata; Q54903949
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1532439;
RX   PubMed=2789474;
RX   PubMed=9162223;
RX   PubMed=15356658;
RX   PubMed=28356514;
RX   PubMed=29533902;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Donor information: Originally the patient was suffering from Hodgkin lymphoma.
DI   NCIt; C37194; Anaplastic large cell lymphoma, ALK-negative
DI   ORDO; Orphanet_300903; ALK-negative anaplastic large cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_H632 ! Mac-2
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 15
//
RX   PubMed=15356658; DOI=10.1038/sj.leu.2403465;
RA   Drexler, Hans Gunther
RA   MacLeod, Roderick A.F.
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   anaplastic large-cell lymphoma.";
RL   Leukemia 18:1569-1571(2004).
//
RX   PubMed=2789474; PMCID=PMC1879862;
RA   Su, Ih-Jen
RA   Kadin, Marshall Edward
RT   "Expression of growth factor/receptor genes in postthymic T cell
RT   malignancies.";
RL   Am. J. Pathol. 135:439-445(1989).
//
RX   PubMed=29533902; DOI=10.1515/hsz-2017-0321;
RA   Drexler, Hans Gunther
RA   Pommerenke, Claudia
RA   Eberth, Sonja
RA   Nagel, Stefan
RT   "Hodgkin lymphoma cell lines: to separate the wheat from the chaff.";
RL   Biol. Chem. 399:511-523(2018).
//
RX   PubMed=1532439; DOI=10.1056/NEJM199204233261704;
RA   Davis, Thomas H.
RA   Morton, Cynthia Casson
RA   Miller-Cassman, Robert
RA   Balk, Steven Paul
RA   Kadin, Marshall Edward
RT   "Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell
RT   lymphoma derived from a common T-cell clone.";
RL   N. Engl. J. Med. 326:1115-1122(1992).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=9162223; DOI=10.1006/cyto.1996.0044;
RA   Marti i Laborda, Rosa Maria
RA   Wasik, Mariusz A.
RA   Kadin, Marshall Edward
RT   "Constitutive secretion of GM-CSF by three different cell lines
RT   derived from a single patient with a progressive cutaneous
RT   lymphoproliferative disorder.";
RL   Cytokine 8:323-329(1996).
//
RX   PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253;
RA   Chen, Jing
RA   Zhang, Yong
RA   Petrus, Michael N.
RA   Xiao, Wen-Ming
RA   Nicolae, Alina
RA   Raffeld, Mark
RA   Pittaluga, Stefania
RA   Bamford, Richard N.
RA   Nakagawa, Masao
RA   Ouyang, Sunny Tian-Yi
RA   Epstein, Alan L.
RA   Kadin, Marshall Edward
RA   Del Mistro, Annarose
RA   Woessner, Richard D.
RA   Jaffe, Elaine Sarkin
RA   Waldmann, Thomas Alexander
RT   "Cytokine receptor signaling is required for the survival of ALK-
RT   anaplastic large cell lymphoma, even in the presence of JAK1/STAT3
RT   mutations.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017).
//