ID   MeT-4A
AC   CVCL_H531
SY   MeT 4A; Met4A; Mesothelial cells transfected with pRSV-T 4A
DR   Wikidata; Q54905321
RX   CelloPub=CLPUB00712;
RX   PubMed=2541616;
RX   PubMed=9175740;
RX   PubMed=19935656;
CC   Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (CelloPub=CLPUB00712; PubMed=19935656).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pRSV-T].
CC   Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
CC   Cell type: Mesothelial cell; CL=CL_0000077.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Transformed cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 11
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RX   CelloPub=CLPUB00712;
RA   Henson J.D.;
RT   "The role of alternative lengthening of telomeres in human cancer.";
RL   Thesis PhD (2006), University of Sydney, Australia.
//
RX   PubMed=2541616;
RA   Ke Y., Reddel R.R., Gerwin B.I., Reddel H.K., Somers A.N.A.,
RA   McMenamin M.G., LaVeck M.A., Stahel R.A., Lechner J.F., Harris C.C.;
RT   "Establishment of a human in vitro mesothelial cell model system for
RT   investigating mechanisms of asbestos-induced mesothelioma.";
RL   Am. J. Pathol. 134:979-991(1989).
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RX   PubMed=9175740; DOI=10.1093/hmg/6.6.921;
RA   Bryan T.M., Marusic L., Bacchetti S., Namba M., Reddel R.R.;
RT   "The telomere lengthening mechanism in telomerase-negative immortal
RT   human cells does not involve the telomerase RNA subunit.";
RL   Hum. Mol. Genet. 6:921-926(1997).
//
RX   PubMed=19935656; DOI=10.1038/nbt.1587;
RA   Henson J.D., Cao Y., Huschtscha L.I., Chang A.C.-M., Au A.Y.M.,
RA   Pickett H.A., Reddel R.R.;
RT   "DNA C-circles are specific and quantifiable markers of
RT   alternative-lengthening-of-telomeres activity.";
RL   Nat. Biotechnol. 27:1181-1185(2009).
//