ID   DC3F/ADII
AC   CVCL_GZ07
SY   DC-3F/ADII; DC-3F/AD II; DC-3F/AD-II
DR   ChEMBL-Cells; CHEMBL3307357
DR   ChEMBL-Targets; CHEMBL614283
DR   PubChem_Cell_line; CVCL_GZ07
DR   TOKU-E; 4117
DR   Wikidata; Q54828626
RX   PubMed=5533992;
RX   PubMed=7907088;
RX   PubMed=11455011;
CC   Selected for resistance to: ChEBI; CHEBI_27666; Actinomycin D (ActD).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4704 ! DC3F
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 26-09-16; Last updated: 19-12-24; Version: 9
//
RX   PubMed=5533992;
RA   Biedler J.L., Riehm H.;
RT   "Cellular resistance to actinomycin D in Chinese hamster cells in
RT   vitro: cross-resistance, radioautographic, and cytogenetic studies.";
RL   Cancer Res. 30:1174-1184(1970).
//
RX   PubMed=7907088; DOI=10.1016/S0021-9258(17)37579-8;
RA   Devine S.E., Melera P.W.;
RT   "Diversity of multidrug resistance in mammalian cells.";
RL   J. Biol. Chem. 269:6133-6139(1994).
//
RX   PubMed=11455011; DOI=10.1124/mol.60.2.254;
RA   Song J., Melera P.W.;
RT   "Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein
RT   that affects drug resistance and cooperates with TM6 to mediate
RT   [125I]iodoarylazidoprazosin labeling.";
RL   Mol. Pharmacol. 60:254-261(2001).
//