ID   UCDK9B1
AC   CVCL_GY10
DR   cancercelllines; CVCL_GY10
DR   Wikidata; Q54989602
RX   DOI=10.1016/j.leukres.2012.09.007;
RX   PubMed=22136758;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a Jurkat derivative (DOI=10.1016/j.leukres.2012.09.007, ICLAC). Originally thought to be of dog origin and to originate from a female Bullmastiff with a lymphoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00540.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Miscellaneous: Samples were supplied to ICLAC for STR profiling by Kent M. (UCSD) and tested by Hall E. (Genetica DNA Laboratories).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ICLAC
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12,13
ST   D13S317: 8,12
ST   D16S539: 11
ST   D18S51: 13,20,21,22
ST   D21S11: 31.2,32.2,33.2,34.2
ST   D3S1358: 15,17
ST   D5S818: 9
ST   D7S820: 8,12
ST   D8S1179: 13,14,15
ST   FGA: 20,21
ST   Penta D: 11,13
ST   Penta E: 10,12
ST   TH01: 6,9.3
ST   TPOX: 8,10
ST   vWA: 18,19
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 21
//
RX   DOI=10.1016/j.leukres.2012.09.007;
RA   Zwingenberger, Allison L.
RA   Vernau, William
RA   Shi, Chang-Ying
RA   Yan, Wen-Sheng
RA   Chen, Xin-Bin
RA   Gordon, Ira K.
RA   Kent, Michael S.
RT   "Corrigendum to 'Development and characterization of 5 canine B-cell
RT   lymphoma cell lines' [Leuk. Res. 36(5) (2011) 601-606].";
RL   Leuk. Res. 37:120-120(2013).
//
RX   PubMed=22136758; DOI=10.1016/j.leukres.2011.11.004; PMCID=PMC5404115;
RA   Zwingenberger, Allison L.
RA   Vernau, William
RA   Shi, Chang-Ying
RA   Yan, Wen-Sheng
RA   Chen, Xin-Bin
RA   Gordon, Ira K.
RA   Kent, Michael S.
RT   "Development and characterization of 5 canine B-cell lymphoma cell
RT   lines.";
RL   Leuk. Res. 36:601-606(2012).
//