ID   LAZ-388
AC   CVCL_GY04
SY   Laz-388; LAZ 388; Laz 388; LAZ388; Laz388
DR   Wikidata; Q54901990
RX   PubMed=2939141;
RX   PubMed=3884668;
RX   PubMed=7108207;
RX   PubMed=8315353;
RX   PubMed=21326318;
CC   From: Lazarus, Herbert; Dana-Farber Cancer Institute; Boston; USA.
CC   Population: Caucasian.
CC   HLA typing: A*01,24; B*22,35 (PubMed=2939141).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1830 ! LAZ-221
SX   Female
AG   24Y
CA   Transformed cell line
DT   Created: 26-09-16; Last updated: 10-09-24; Version: 10
//
RX   PubMed=2939141; DOI=10.4049/jimmunol.136.11.4311;
RA   Pesando J.M., Graf L.;
RT   "Differential expression of HLA-DR, -DQ, and -DP antigens on malignant
RT   B cells.";
RL   J. Immunol. 136:4311-4318(1986).
//
RX   PubMed=3884668; DOI=10.1172/JCI111794; PMCID=PMC423627;
RA   Hercend T., Griffin J.D., Bensussan A., Schmidt R.E., Edson M.A.,
RA   Brennan A., Murray C., Daley J.F., Schlossman S.F., Ritz J.;
RT   "Generation of monoclonal antibodies to a human natural killer clone.
RT   Characterization of two natural killer-associated antigens, NKH1A and
RT   NKH2, expressed on subsets of large granular lymphocytes.";
RL   J. Clin. Invest. 75:932-943(1985).
//
RX   PubMed=7108207; DOI=10.4049/jimmunol.129.3.1299;
RA   Hercend T., Meuer S.C., Reinherz E.L., Schlossman S.F., Ritz J.;
RT   "Generation of a cloned NK cell line derived from the 'null cell'
RT   fraction of human peripheral blood.";
RL   J. Immunol. 129:1299-1305(1982).
//
RX   PubMed=8315353; DOI=10.1002/jlb.53.6.697;
RA   Woolfrey A.E., Andersen L.C., Shewey L., Chung J., Nepom G.T.;
RT   "Analysis of differential HLA-DQB expression in autologous B cell
RT   lines.";
RL   J. Leukoc. Biol. 53:697-706(1993).
//
RX   PubMed=21326318; DOI=10.1038/gene.2010.77; PMCID=PMC3107363;
RA   Majumder P., Boss J.M.;
RT   "DNA methylation dysregulates and silences the HLA-DQ locus by
RT   altering chromatin architecture.";
RL   Genes Immun. 12:291-299(2011).
//