ID   4T1.2
AC   CVCL_GR32
DR   ATCC; CRL-3406
DR   ChEMBL-Cells; CHEMBL4483001
DR   ChEMBL-Targets; CHEMBL4483221
DR   PubChem_Cell_line; CVCL_GR32
DR   Wikidata; Q54603658
RX   PubMed=10411109;
RX   PubMed=15671244;
CC   Characteristics: High propensity to metastasize spontaneously to bone, causing fractures and/or hindlimb paralysis (ATCC=CRL-3406).
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: BALB/cfC3H.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0125 ! 4T1
SX   Female
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 29-06-23; Version: 7
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RX   PubMed=10411109; DOI=10.1023/A:1006689719505;
RA   Lelekakis M., Moseley J.M., Martin T.J., Hards D., Williams E., Ho P.,
RA   Lowen D., Javni J., Miller F.R., Slavin J., Anderson R.L.;
RT   "A novel orthotopic model of breast cancer metastasis to bone.";
RL   Clin. Exp. Metastasis 17:163-170(1999).
//
RX   PubMed=15671244; DOI=10.1158/1541-7786.1.3.1;
RA   Eckhardt B.L., Parker B.S., van Laar R.K., Restall C.M., Natoli A.L.,
RA   Tavaria M.D., Stanley K.L., Sloan E.K., Moseley J.M., Anderson R.L.;
RT   "Genomic analysis of a spontaneous model of breast cancer metastasis
RT   to bone reveals a role for the extracellular matrix.";
RL   Mol. Cancer Res. 3:1-13(2005).
//