ID   HepT1
AC   CVCL_G003
DR   Cosmic; 869287
DR   Cosmic; 1237545
DR   Wikidata; Q54882877
RX   PubMed=8606490;
RX   PubMed=10934159;
RX   PubMed=12704668;
CC   Characteristics: Tumorigenic. Injection into nude mice gives rise to subcutaneous tumors (PubMed=8606490).
CC   Doubling time: 1-2 days (PubMed=8606490).
CC   Karyotypic information: Near tetraploid karyotype (PubMed=8606490).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   2Y10M
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 12
//
RX   PubMed=8606490;
RA   Pietsch T., Fonatsch C., Albrecht S., Maschek H., Wolf H.K.,
RA   von Schweinitz D.;
RT   "Characterization of the continuous cell line HepT1 derived from a
RT   human hepatoblastoma.";
RL   Lab. Invest. 74:809-818(1996).
//
RX   PubMed=10934159; DOI=10.1016/S0002-9440(10)64567-1; PMCID=PMC1850131;
RA   Weber R.G., Pietsch T., von Schweinitz D., Lichter P.;
RT   "Characterization of genomic alterations in hepatoblastomas. A role
RT   for gains on chromosomes 8q and 20 as predictors of poor outcome.";
RL   Am. J. Pathol. 157:571-578(2000).
//
RX   PubMed=12704668; DOI=10.1002/ijc.11082;
RA   Scheil S., Hagen S., Bruderlein S., Leuschner I., Behnisch W.,
RA   Moller P.;
RT   "Two novel in vitro human hepatoblastoma models, HepU1 and HepU2, are
RT   highly characteristic of fetal-embryonal differentiation in
RT   hepatoblastoma.";
RL   Int. J. Cancer 105:347-352(2003).
//