ID   T560.2.F7
AC   CVCL_F727
DR   Wikidata; Q54971591
RX   PubMed=1535783;
RX   PubMed=10433101;
RX   PubMed=11683378;
CC   Characteristics: Secretes polyreactive IgG2a antibodies whose known ligands include phosphorylcholine, 2,4,6,trinitrophenyl-determinant, human TNF-beta and polystyrene. Can switches spontaneously from IgG2a to IgA (PubMed=10433101; PubMed=11683378).
CC   Breed/subspecies: B10 x B10.H-2aH-4b.
DI   NCIt; C21602; Mouse lymphoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F726 ! T560.2
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 14-08-25; Version: 7
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RX   PubMed=1535783; DOI=10.1093/intimm/4.2.107;
RA   Rao, T. Dharma
RA   Maghazachi, Azzam A.
RA   Faria, Ana Maria Caetano
RA   Basch, Ross S.
RA   Phillips-Quagliata, Julia M.
RT   "T560: an (H-2b x H-2a) F1 hybrid, phosphorylcholine (PC)-binding,
RT   murine B cell lymphoma that bears receptors for IgA and IgG, presents
RT   antigen and secretes IL-4.";
RL   Int. Immunol. 4:107-118(1992).
//
RX   PubMed=10433101; DOI=10.3109/08916939908998536;
RA   Phillips-Quagliata, Julia M.
RA   Faria, Ana Maria Caetano
RA   Han, Jing-Kang
RA   Spencer, Deborah H.
RA   Haughton, Geoffrey
RA   Casali, Paolo
RT   "The IgG2a/IgA produced by the murine T560 B lymphoma that arose
RT   during a graft-versus-host reaction is polyreactive and somatically
RT   mutated.";
RL   Autoimmunity 29:215-233(1999).
//
RX   PubMed=11683378; DOI=10.3109/08916930109008046;
RA   Phillips-Quagliata, Julia M.
RA   Faria, Ana Maria Caetano
RA   Han, Jing-Kang
RA   Spencer, Deborah H.
RA   Haughton, Geoffrey
RA   Casali, Paolo
RT   "IgG2a and IgA co-expression by the natural autoantibody-producing
RT   murine B lymphoma T560.";
RL   Autoimmunity 33:181-197(2001).
//