ID   TY08
AC   CVCL_F712
DR   Wikidata; Q54973450
RX   DOI=10.1111/cen3.12001;
RX   PubMed=20458752;
CC   Population: Japanese.
CC   Characteristics: Exhibits a robust proliferation at the permissive temperature of 33 Celsius. Cell growth is arrested at 37 Celsius (PubMed=20458752).
CC   Characteristics: These cells do not grow beyond the 16th to 18th passages, even under the permissive temperature (DOI=10.1111/cen3.12001).
CC   Doubling time: ~3 days (PubMed=20458752).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA58].
CC   Derived from site: In situ; Brain, microvascular endothelium; UBERON=UBERON_0000955+UBERON_0008339.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Conditionally immortalized cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 10
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RX   DOI=10.1111/cen3.12001;
RA   Sano Y., Kashiwamura Y., Abe M., Dieu L.-H., Huwyler J., Shimizu F.,
RA   Haruki H., Maeda T., Saito K., Tasaki A., Kanda T.;
RT   "Stable human brain microvascular endothelial cell line retaining its
RT   barrier-specific nature independent of the passage number.";
RL   Clin. Exp. Neuroimmunol. 4:92-103(2013).
//
RX   PubMed=20458752; DOI=10.1002/jcp.22232;
RA   Sano Y., Shimizu F., Abe M., Maeda T., Kashiwamura Y., Ohtsuki S.,
RA   Terasaki T., Obinata M., Kajiwara K., Fujii M., Suzuki M., Kanda T.;
RT   "Establishment of a new conditionally immortalized human brain
RT   microvascular endothelial cell line retaining an in vivo blood-brain
RT   barrier function.";
RL   J. Cell. Physiol. 225:519-528(2010).
//