ID   K1735-M2
AC   CVCL_F684
SY   K-1735 M2; K-1735 M-2; K-1735-M-2; K1735M2; K1735 Met 2; M-2; K-1735 subclone M2
DR   Wikidata; Q54899262
RX   PubMed=1826230;
RX   PubMed=3370643;
RX   PubMed=3756870;
RX   PubMed=6750200;
RX   PubMed=11820393;
WW   Provider; MD Anderson CCAC; -; https://www.mdanderson.org/content/dam/mdanderson/documents/core-facilities/Cytogenetics-and-Cell-Authentication-Core/Cell%20Line%20List%203-23-2022.pdf
CC   Characteristics: Highly tumorigenic and metastatic. Derived from a lung metastasis produced by the parent tumor-growing subcutaneously.
CC   Sequence variation: Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Breed/subspecies: C3H/HeN.
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F828 ! K1735
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 8
//
RX   PubMed=1826230;
RA   Zhang R.-D., Price J.E., Schackert G., Itoh K., Fidler I.J.;
RT   "Malignant potential of cells isolated from lymph node or brain
RT   metastases of melanoma patients and implications for prognosis.";
RL   Cancer Res. 51:2029-2035(1991).
//
RX   PubMed=3370643;
RA   Schackert G., Fidler I.J.;
RT   "Site-specific metastasis of mouse melanomas and a fibrosarcoma in the
RT   brain or meninges of syngeneic animals.";
RL   Cancer Res. 48:3478-3484(1988).
//
RX   PubMed=3756870;
RA   Fidler I.J., Talmadge J.E.;
RT   "Evidence that intravenously derived murine pulmonary melanoma
RT   metastases can originate from the expansion of a single tumor cell.";
RL   Cancer Res. 46:5167-5171(1986).
//
RX   PubMed=6750200; DOI=10.1093/jnci/69.4.975;
RA   Talmadge J.E., Fidler I.J.;
RT   "Enhanced metastatic potential of tumor cells harvested from
RT   spontaneous metastases of heterogeneous murine tumors.";
RL   J. Natl. Cancer Inst. 69:975-980(1982).
//
RX   PubMed=11820393; DOI=10.1007/s002490100173;
RA   Ahammer H., DeVaney T.T.J., Tritthart H.A.;
RT   "Fractal dimension of K1735 mouse melanoma clones and spheroid
RT   invasion in vitro.";
RL   Eur. Biophys. J. 30:494-499(2001).
//