ID   RAW-D
AC   CVCL_F681
SY   RAW264 cell D; D clone; RAW264.7D; RAW264 cell Differentiation
DR   Wikidata; Q54949256
RX   PubMed=14709158;
RX   PubMed=15452179;
RX   PubMed=15812249;
CC   Characteristics: Differentiates into osteoclast-like multinucleated cells at a very high rate even at low concentrations of RANKL (PubMed=14709158).
CC   Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: Macrophage; CL=CL_0000235.
CC   Breed/subspecies: BALB/c.
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0493 ! RAW 264.7
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 29-06-23; Version: 11
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RX   PubMed=14709158; DOI=10.1677/joe.0.1800193;
RA   Watanabe T., Kukita T., Kukita A., Wada N., Toh K., Nagata K.,
RA   Nomiyama H., Iijima T.;
RT   "Direct stimulation of osteoclastogenesis by MIP-1alpha: evidence
RT   obtained from studies using RAW264 cell clone highly responsive to
RT   RANKL.";
RL   J. Endocrinol. 180:193-201(2004).
//
RX   PubMed=15452179; DOI=10.1084/jem.20040518;
RA   Kukita T., Wada N., Kukita A., Kakimoto T., Sandra F., Toh K.,
RA   Nagata K., Iijima T., Horiuchi M., Matsusaki H., Hieshima K.,
RA   Yoshie O., Nomiyama H.;
RT   "RANKL-induced DC-STAMP is essential for osteoclastogenesis.";
RL   J. Exp. Med. 200:941-946(2004).
//
RX   PubMed=15812249; DOI=10.1089/jir.2005.25.227;
RA   Nomiyama H., Egami K., Wada N., Tou K., Horiuchi M., Matsusaki H.,
RA   Miura R., Yoshie O., Kukita T.;
RT   "Identification of genes differentially expressed in osteoclast-like
RT   cells.";
RL   J. Interferon Cytokine Res. 25:227-231(2005).
//