ID   EDITGENE NCI-H460-Cas9
AC   CVCL_F5QC
SY   NCI-H460-Cas9
DR   EDITGENE; EDC01268
CC   Population: Caucasian.
CC   Characteristics: Growth mode Adherent.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): EDITGENE=EDC01268
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 13
ST   D16S539: 9
ST   D5S818: 9,10
ST   D7S820: 9,12
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0459 ! NCI-H460
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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