ID   EDITGENE S1PR1 Knockout U251 MG Cell Line
AC   CVCL_F5C0
SY   S1PR1 Knockout U251 MG Cell Line
DR   EDITGENE; EDC07681
CC   Population: Caucasian.
CC   Characteristics: Growth mode Adherent.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3165; S1PR1.
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0021 ! U-251MG
SX   Male
AG   75Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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