ID   FEOXCS ESC clone 1
AC   CVCL_F4XH
SY   FEOXCS; clone 1; FEOXCS-238-8N
RX   PubMed=41120533;
CC   Characteristics: Expresses the FEOX sensor, composed of mTagBFP2 fused to a FBXL5 hemerythrin-like iron/oxygen-sensing domain, together with mCherry as control reporter.
CC   Genetic integration: Method=PiggyBac transposition; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
CC   Genetic integration: Method=PiggyBac transposition; Gene=FPbase; ZO7NN; mTagBFP2 (Note=Blue fluorescent protein derived from eqFP578).
CC   Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:13602; FBXL5 (Note=AA 1-161 = hemerythrin-like).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: C57BL/6J x 129S4/SvJae.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_C865 ! v6.5
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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RX   PubMed=41120533; DOI=10.1038/s41598-025-20428-5; PMCID=PMC12541023;
RA   Sangokoya, Carolyn
RT   "The genetically encoded biosensor FEOX is a molecular gauge for
RT   cellular iron environment dynamics at single cell resolution.";
RL   Sci. Rep. 15:36596-36596(2025).
//