ID   HyCyte A-549 stable cell line for hGSDME overexpression
AC   CVCL_F4UU
SY   A-549 stable cell line for hGSDME overexpression
DR   Hysigen; CGSC-M35851
CC   Population: Caucasian.
CC   Characteristics: Transfected with pPB[Exp]-EF1A>EGFP-CAG>hGSDME[NM_001127453.2]-PGK>Puro.
CC   Doubling time: 36-48 hours (Hysigen=CGSC-M35851).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; EGFP.
CC   Genetic integration: Method=PiggyBac transposition; Gene=HGNC; HGNC:2810; GSDME.
CC   Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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