ID   HyCyte NB4 stable cell line for hBCL6B overexpression
AC   CVCL_F4SQ
SY   NB4 stable cell line for hBCL6B overexpression
DR   Hysigen; CGSC-M33831
CC   Population: Caucasian.
CC   Characteristics: Transduced with pLV[Exp]-CMV>hBCL6B[NM_181844.4]-EF1A>copGFP:T2A:Puro-WPRE.
CC   Doubling time: 18-24 hours (Hysigen=CGSC-M33831).
CC   Sequence variation: Gene fusion; HGNC; HGNC:9113; PML + HGNC; HGNC:9864; RARA; Name(s)=PML-RARA (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala18Asp (c.53C>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; EGFP.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1002; BCL6B.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3182; Acute promyelocytic leukemia with PML-RARA
DI   ORDO; Orphanet_520; Acute promyelocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0005 ! NB4
SX   Female
AG   23Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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