ID   HyCyte OVCAR-8 KO-hSMARCA4
AC   CVCL_F4J4
SY   hSMARCA4 knockout OVCAR-8 cell line
DR   Hysigen; CGKO-M3490
CC   Population: Caucasian.
CC   Doubling time: 24-36 hours (Hysigen=CGKO-M3490).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11100; SMARCA4.
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gln26Arg (c.77A>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:3430; ERBB2; Simple; p.Gly776Val (c.2327G>T); ClinVar=VCV000163410; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Pro121His (c.362C>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1629 ! OVCAR-8
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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