ID   HyCyte BT-549 KO-hPDK1
AC   CVCL_F4IV
SY   hPDK1 knockout BT-549 cell line
DR   Hysigen; CGKO-M2168
CC   Population: Caucasian.
CC   Doubling time: 36-48 hours (Hysigen=CGKO-M2168).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8809; PDK1.
CC   Sequence variation: Gene fusion; HGNC; HGNC:2092; CLTC + HGNC; HGNC:29559; VMP1; Name(s)=CLTC-VMP1 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val275fs*1 (c.821delG) (p.W274fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_607del343; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>C); ClinVar=VCV000406598; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1092 ! BT-549
SX   Female
AG   72Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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