ID   HyCyte MDA-MB-453 KO-hCPB1
AC   CVCL_F4GL
SY   hCPB1 knockout MDA-MB-453 cell line
DR   Hysigen; CGKO-M3469
CC   Population: Caucasian.
CC   Doubling time: 48-72 hours (Hysigen=CGKO-M3469).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:2299; CPB1.
CC   Sequence variation: Mutation; HGNC; HGNC:644; AR; Simple; p.Gln868His (c.2604G>T); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1748; CDH1; Simple; p.Trp638Ter (c.1913G>A); ClinVar=VCV000599651; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu307Lys (c.919G>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Unexplicit; Ex10-11del; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Pericardial effusion; UBERON=UBERON_0002409.
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0418 ! MDA-MB-453
SX   Female
AG   48Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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