ID   965729-122-R-J2-PDC
AC   CVCL_F4DJ
DR   NCI-PDMR; 8077
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 28 hours (NCI-PDMR=8077).
CC   HLA typing: A*01:01,01:01; B*15:17,15:17; C*07:01,07:01 (NCI-PDMR=8077).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=8077).
CC   Sequence variation: Mutation; HGNC; HGNC:950; BAP1; Simple; p.R385* (c.1153C>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=8077).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.X153_splice (c.458-2A>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=8077).
CC   Sequence variation: Mutation; HGNC; HGNC:7773; NF2; Simple; p.P275Nfs*22 (c.821_822dup); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=8077).
CC   Sequence variation: Mutation; HGNC; HGNC:17101; SUZ12; Simple; p.L564Sfs*5 (c.1688dup); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4761 (NCI-PDMR=8077).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Retroperitoneal lymph node; UBERON=UBERON_0035371.
ST   Source(s): NCI-PDMR=8077
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 18
ST   D19S433: 14,15
ST   D21S11: 30
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 10,13
ST   D7S820: 10,12
ST   D8S1179: 15
ST   FGA: 24.2
ST   TH01: 8
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C6975; Papillary renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   59Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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