ID   693688-280-R-J1-PDC
AC   CVCL_F4DF
DR   NCI-PDMR; 3552
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 23 hours (NCI-PDMR=3552).
CC   HLA typing: A*02:01,02:01; B*35:03,51:01; C*04:01,04:01 (NCI-PDMR=3552).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=3552).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.R564* (c.1690C>T); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3552).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.L1488Yfs*19 (c.4463del); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=3552).
CC   Sequence variation: Mutation; HGNC; HGNC:18037; ARID2; Simple; p.S1351Vfs*3 (c.4051del); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.455 (NCI-PDMR=3552).
CC   Sequence variation: Mutation; HGNC; HGNC:28434; FAM58A; Simple; p.C181* (c.542_543delinsAG); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.4679 (NCI-PDMR=3552).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.R273H (c.818G>A); Zygosity=Homozygous; Note=Oncogenic, variant allele frequency: 1 (NCI-PDMR=3552).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): NCI-PDMR=3552
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 9,10
ST   D16S539: 9,11
ST   D18S51: 18
ST   D19S433: 13
ST   D21S11: 32.2
ST   D2S1338: 24,26
ST   D3S1358: 15,20
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 9,13
ST   FGA: 25
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 14,16
DI   NCIt; C3915; Small Cell Neuroendocrine Carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   62Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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