ID   268233-264-R-J1-PDC
AC   CVCL_F4D8
DR   NCI-PDMR; 12289
CC   Part of: NCI Patient-Derived Model Repository.
CC   Population: African; Yoruba in Ibadan, Nigeria (YRI).
CC   Characteristics: tumorigenic in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Characteristics: Established from a patient-derived xenograft (PDX) in NOD/SCID/IL2RgammaNULL (NSG) mice.
CC   Doubling time: 35 hours (NCI-PDMR=12289).
CC   HLA typing: A*30:02,68:01; B*08:01,44:03; C*03:04,04:01 (NCI-PDMR=12289).
CC   Microsatellite instability: Stable (MSS) (NCI-PDMR=12289).
CC   Sequence variation: Mutation; HGNC; HGNC:1748; CDH1; Simple; p.A617T (c.1849G>A); Zygosity=Heterozygous; Note=Likely Oncogenic, variant allele frequency: 0.3843 (NCI-PDMR=12289).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.G12D (c.35G>A); Zygosity=Heterozygous; Note=Oncogenic, variant allele frequency: 0.5465 (NCI-PDMR=12289).
CC   Sequence variation: Mutation; HGNC; HGNC:7326; MSH3; Simple; p.A60Pfs*23 (c.177_178insCCCCCAGC); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12289).
CC   Sequence variation: Mutation; HGNC; HGNC:7326; MSH3; Simple; p.A61Pfs*25 (c.180_181insCCCA); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12289).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.S183* (c.548C>G); Zygosity=Homozygous; Note=Likely Oncogenic, variant allele frequency: 1 (NCI-PDMR=12289).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Nose, nasal cavity, left maxillary sinus; UBERON=UBERON_0001764.
ST   Source(s): NCI-PDMR=12289
ST   Amelogenin: X
ST   CSF1PO: 13
ST   D13S317: 12
ST   D16S539: 9
ST   D18S51: 13,22
ST   D19S433: 13,14.2
ST   D21S11: 36
ST   D2S1338: 21
ST   D3S1358: 18
ST   D5S818: 8
ST   D7S820: 10,12
ST   D8S1179: 14
ST   FGA: 26
ST   TH01: 8
ST   TPOX: 7,9
ST   vWA: 20,22
DI   NCIt; C68611; Sinus Squamous Cell Carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   58Y
CA   Cancer cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
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