ID   EPC1
AC   CVCL_F4C4
RX   PubMed=12435727;
CC   Characteristics: Displays normal cell morphology, cytogenetics, and biochemistry. Expresses cytokeratins 5 and 14, lacks p53 mutation.
CC   Characteristics: Can be induced to differentiate into stratified squamous epithelium in a postconfluent state or with high calcium concentration.
CC   Senescence: Senesces after 40–44 population doublings.
CC   Karyotypic information: Normal diploid karyotype (PubMed=12435727).
CC   Derived from site: In situ; Epithelium of esophagus; UBERON=UBERON_0001976.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_F4C3 ! EPC2
SX   Sex unspecified
AG   Age unspecified
CA   Finite cell line
DT   Created: 25-06-26; Last updated: 25-06-26; Version: 1
CH   CVCL_F4C5 ! EPC1-EGFR
CH   CVCL_F4C6 ! EPC1-GFP
//
RX   PubMed=12435727; DOI=10.1074/jbc.M209148200;
RA   Andl, Claudia D.
RA   Mizushima, Takaaki
RA   Nakagawa, Hiroshi
RA   Oyama, Kenji
RA   Harada, Hideki
RA   Chruma, Katerina
RA   Herlyn, Meenhard
RA   Rustgi, Anil K.
RT   "Epidermal growth factor receptor mediates increased cell
RT   proliferation, migration, and aggregation in esophageal keratinocytes
RT   in vitro and in vivo.";
RL   J. Biol. Chem. 278:1824-1830(2003).
//